Add to ORKGMultiple immunohistochemical stains, including cytokeratin (CK)5/6, are used in a panel format to identify “basal-like ” carcinomas. We set out to determine the sensitivity and specificity of the CK5 antibody (clone XM26) and compared its expression with that of CK5/6 (clone D5/16B4) in a variety of breast carcinoma cases. The study was performed on 3 breast carcinoma tissue microarrays (TMAs). TMA-1 consisted of 59 consecutive breast carcinoma cases. TMA-2 (n = 16) and TMA-3 (n = 11) consisted of basal-like breast carcinomas previously characterized morphologically and immunohistochemically at our institution. Of the 86 total cases, 20 were positive for CK5 and CK5/6, 14 were positive for CK5 only, and 52 were negative for both. The sensit...
Introduction: The most suitable immunohistochemical criterion to identify basal-like breast carcinom...
Introduction: The most suitable immunohistochemical criterion to identify basal-like breast carcinom...
BACKGROUND: Cytokeratins are non-contractile intermediate filaments engaged in anchoring and structu...
Human breast carcinomas represent a heterogeneous group of tumors diverse in behavior, outcome, and ...
Breast ducts contain two types of epithelial cells, inner luminal cells and outer basal/ myoepitheli...
Objective:Gene expression studies have revealed several molecular subtypes of breast carcinoma with ...
Objectives: The aim of this study was to use immunohistochemistry to differentiate solid papillary c...
Cytokeratin 5/6 (CK 5/6) immunoreactivity has been observed in the vast majority of cases of maligna...
p63, cytokeratin (CK) 5/6 and CK 14 have been employed in diagnostic pathology as markers of basal, ...
In recent studies, Bocker and colleagues described a population of cells in paraffin wax sections of...
20 years as structural marker proteins specific for epithelial cells. Recent expression profiling an...
Introduction: Fibroadenomas (FAs) are the most common benign tumors in the breast. Described as a bi...
<p>A case with higher CKAP2-positive cells (A) showed higher Ki-67-positive cells (B). A case with l...
<p>CKAP2-positive cells are rare in normal breast ductal cells (A), but present variably in breast c...
We tested the hypothesis that the coordinate expression of cytokeratin 7 (CK 7) and cytokeratin 20 (...
Introduction: The most suitable immunohistochemical criterion to identify basal-like breast carcinom...
Introduction: The most suitable immunohistochemical criterion to identify basal-like breast carcinom...
BACKGROUND: Cytokeratins are non-contractile intermediate filaments engaged in anchoring and structu...
Human breast carcinomas represent a heterogeneous group of tumors diverse in behavior, outcome, and ...
Breast ducts contain two types of epithelial cells, inner luminal cells and outer basal/ myoepitheli...
Objective:Gene expression studies have revealed several molecular subtypes of breast carcinoma with ...
Objectives: The aim of this study was to use immunohistochemistry to differentiate solid papillary c...
Cytokeratin 5/6 (CK 5/6) immunoreactivity has been observed in the vast majority of cases of maligna...
p63, cytokeratin (CK) 5/6 and CK 14 have been employed in diagnostic pathology as markers of basal, ...
In recent studies, Bocker and colleagues described a population of cells in paraffin wax sections of...
20 years as structural marker proteins specific for epithelial cells. Recent expression profiling an...
Introduction: Fibroadenomas (FAs) are the most common benign tumors in the breast. Described as a bi...
<p>A case with higher CKAP2-positive cells (A) showed higher Ki-67-positive cells (B). A case with l...
<p>CKAP2-positive cells are rare in normal breast ductal cells (A), but present variably in breast c...
We tested the hypothesis that the coordinate expression of cytokeratin 7 (CK 7) and cytokeratin 20 (...
Introduction: The most suitable immunohistochemical criterion to identify basal-like breast carcinom...
Introduction: The most suitable immunohistochemical criterion to identify basal-like breast carcinom...
BACKGROUND: Cytokeratins are non-contractile intermediate filaments engaged in anchoring and structu...